Dermafine-MD
DERMAFINE-MD 6 OZ. BOTTLE
RETAIL PRICE: $80. FREE SHIPPING IN US!
SITE UPDATE : 07/01/2008
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Dermafine-MD
Dermafine-MD is a micro active formula to help reduce the appearance of strech
marks, wrinkles and age spots. Dermafine-MD gives you the ultimate repairing
micro emulsion formula for rebuilding new skin and reducing the appearance of
strech marks, wrinkles and age spots and even helps tighten and smooth your skin
while it firms and nourishes it.
Dermafine-MD is a topical stretch mark cream with amazing technological
anti-wrinkle properties. When applied to your face, it requires no painful
peels,implants, or expensive injections, swelling, black and blue marks,
puffiness and other complications that result from treatments and procedures
such as Botox®.
Dermafine-MD retards the aging of cells and mimics Botox® treatments without
the discomfort and expense!
Dermafine-MD's Micro Active formula penetrates the skin so effectively that you
will see results within weeks if not days! It outperforms products with Retinol
and Vitamin C and cost much less that other skin treatments such as Botox®!
Dermafine-MD has an exclusive proprietary blend to increase its effectiveness.
To achieve these results Dermafine-MD uses a patented pentapeptide (25% more
than Strivectin-SD) that has produced results unseen in the cosmetic industry.
Together with a host of the industry's best anti-aging ingredients our blend
targets major problem areas like sagging skin, skin discoloration, dryness and
rough skin; not just wrinkles. And you can be sure to see these results
immediately! Dermafine-MD has come to be known as the safe alternative to Botox®,
providing equal or better results without the risk.
Palmitoyl pentapeptide (a.k.a palmitoyl
oligopeptide) is a new skin rejuvenation compound developed by the corporations
Sederma SA and Proctor & Gamble. Lately, it has generated
a lot of media buzz and has been included in a variety of pricey skin care
formulas.
Chemically speaking, palmitoyl
pentapeptide is a relatively small molecule (five amino acids linked together
and attached to a fatty acid) structurally related to the precursor of collagen
type I (a.k.a. procollagen type I). Researchers found that when added to the
culture of fibroblasts (the key skin cells), palmitoyl pentapeptide stimulated
the synthesis of the key constituents of the skin matrix: collagen, elastin and
glucosamnoglycans. How exactly palmitoyl pentapeptide did that remains unclear,
although a number of theories exist.
So far, clinical data are
encouraging. One study demonstrated that palmitoyl pentapeptide was as effective
as retinol in repairing sun-damaged skin but was devoid of side-effects. Most
other studies showed at least some improvement in various objective and
subjective measures of wrinkles. No side effects have been reported.
Palmitoyl pentapeptide may also be
considered as a nonirritating fall back option for people who develop skin
irritation in response to retinoids or alpha-hydroxy acids.
There is a large price variation
between different palmitoyl pentapeptide products, although none are dirt-cheap.
However, the price does not always reflect the concentration of the active
ingredient. It might reflect prestige of the brand, advertising overhead,
sophistication of packaging and so forth. Be wise. Make sure you are paying a
fair price per unit of the pentapeptide.
Study:
The first study, conducted by Dr. Karl Lintner,
with Sederma SA in Paris, France, and colleagues, examined the effects of
palmitoyl pentapeptide 3 ppm versus retinol 700 ppm on photo-aged skin. This
double-blind half-face study enrolled 16 healthy women. For four months, they
applied a cream containing 700 ppm of retinol to the crow's feet area on one
side of the face and the same base cream containing 3 ppm of palmitoyl
pentapeptide to the other side of the face.
Patients applied the creams once daily for the first two months of the trial,
then twice daily during months 3 and 4.
Significant improvement of the skin profile (determined by profilometry of
wrinkle depth, length, volume, roughness) for patients using the peptide was
observed at the two-month evaluation versus baseline with further improvement
versus baseline after four months.
Dermatological scoring as well as image analysis confirmed a decrease in overall
roughness and deep facial wrinkles with both treatments after four months.
Although skin thickness increased by an average of 9 percent after four months
for both treatments, the two-month data suggested that palmitoyl pentapeptide
thickened the skin about 1.5 times faster than retinol.
Palmitoyl pentapeptide did not cause the inflammatory reactions frequently
associated with retinol treatment.
Overall, the results suggest that palmitoyl pentapeptide is as effective as
retinol at regenerating the skin but without the irritation that often occurs
secondary to retinoid use, Dr. Lintner said.
Dr. Lintner and Dr. Jean Revuz, with Mondor Hospital in Paris and the current
president of the WCD, presented the results of the second study, which examined
the effects of palmitoyl pentapeptide 5 ppm on the structure of elastin and
collagen IV in 49 women with photo-aged skin.
Over the course of the four-month, blinded study, the women who used 5 ppm of
palmitoyl pentapeptide had substantial improvements in skin roughness, wrinkle
volume, and wrinkle depth. Skin biopsies conducted on six patients indicated
that palmitoyl pentapeptide triggered growth in elastin and collagen IV and
enhanced the structure of elastin and collagen IV.
The researchers note that the peptide was not associated with any side effects
and was "a safe and potent alternative to Retinoids in wrinkle repair."
Palmitoyl pentapeptide is a lipophilic modified peptide that is presently being
investigated as an anti-aging ingredient. The peptide was developed by Sederma
SA and is being tested by Sederma and Procter & Gamble Company in Cincinnati,
Ohio.
Both studies were supported by Sederma SA.
General Guidelines:
• 2 to 4 Weeks - for mild or minor marks.
• 5 to 10 Weeks - for medium and darker marks.
• 11+ Weeks - for significant repair of severely damaged skin.
Dermafine-MD offers immediate results targeting
the category of fine lines, wrinkles and crows feet and can remove 10-15 years
from your complexion. The isolates in Dermafine-MD were shown in clinical
studies to dramatically improve skin smoothness and decrease wrinkle depth as it
increases collagen and elastin. It was shown to be even more effective than
Retinol or Vitamin C in reducing fine facial lines and wrinkles while
diminishing the signs of aging.
When comparing your options for anti-wrinkle
creams Dermafine clearly comes out on top. There are a number of creams on
the market such as Strivectin-SD that cost $135 dollars but none offer the
effectiveness and value that Dermafine provides. This product is a
powerful anti-wrinkle product which is safe and effective. There is no
need to undergo expensive and painful surgery or shots which offers risky and
far from permanent results. More importantly the continual use of
Dermafine-MD will gradually rejuvenate the tone and texture of your skin to
leave you long lasting effects. If you're still not convinced, read some of the
testimonials:
"After using Dermafine-MD for about a week and a
half I began to receive a lot of compliments from my friends. They told me
that I looked younger and more vibrant. I definitely noticed an increase
in the smoothness of my face and elasticity of my skin. Now that I am
using this formula I look and feel great!"
Sharon R.
Cincinatti, OH
"I'm 47 years old and I've always taken good care
of my skin. Since I got married 28 years ago I've gone through dozens of
different products. I was so disappointed when I started noticing that my skin
color was uneven. The dermatologist prescribed a topical cream and medicine but
three years later the improvement was small. I found your product online two
months ago and it's amazing how much better my skin looks. Even my dermatologist
is impressed! I haven't felt this good about myself in years! Thank you."
Terry A.
San Diego, CA
"God I hate crow's feet!! They just wouldn't go
away and they would make me look so old. I paid over $200 for a cream by
________ [name omitted due to trademark considerations] and at first it worked
but they came back. I really thought I had tried everything. It's funny it was
my mom who told me to try you guys. It really made a difference on her and I
thought Dermafine had to work on me. Well it really did. I finally got rid of
these ugly crow's feet for good! I've been using Dermafine for 4 months and so
far so good."
Carol S.
Hoboken, NJ
